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World Community Grid Forums
Category: Completed Research
Forum: OpenZika
Thread: Interesting News Articles About Zika |
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Thread Status: Active Total posts in this thread: 154
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Richard Mitnick
Veteran Cruncher USA Joined: Feb 28, 2007 Post Count: 583 Status: Offline Project Badges: 
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I tired to access the link at BOINC and leave this response, I could not, no current credit.
----------------------------------------The poster should have included a link to an article or science paper and did not. Maybe someone who can access the thread and leave a reply will ask the poster to better identify his information. I think OpenZika should see it. |
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SekeRob
Master Cruncher Joined: Jan 7, 2013 Post Count: 2741 Status: Offline |
If you talk about that seti link, which then goes nowhere, nothing new about the bacterium plant on the aegis mosquito.[ot]Pity you don't crunch any more, [/ot]
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Maxxina
Advanced Cruncher Joined: Jan 5, 2008 Post Count: 125 Status: Offline Project Badges: 
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Nah, it was propably on me :)
Sorry me bad. this is better version : ) http://jid.oxfordjournals.org/content/early/2016/05/26/infdis.jiw226.long |
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littlepeaks
Veteran Cruncher USA Joined: Apr 28, 2007 Post Count: 748 Status: Offline Project Badges: 
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One of the current limitations in projects run on WCG is using libraries of small molecules (<600 molecular weight, I believe) to try to interact with the disease-causing organisms. In May, IBM announced the discovery of a new macromolecule (large molecule) that may be effective against Zika, Ebola, and Dengue Fever.
----------------------------------------I have often wondered why WCG never had a project to search for macromolecules to control diseases (it may be a modeling software limitation). I believe there is one medicine for HIV that uses macromolecules. Anyway, before I go off into the "verbose mode", IBM's announcement may be accessed at http://www.ibn.a-star.edu.sg/images/cms_press/press_121.pdf IBM's announcement is dated May 11, 2016. [Edit 1 times, last edit by littlepeaks at Jun 16, 2016 6:27:07 PM] |
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KLiK
Master Cruncher Croatia Joined: Nov 13, 2006 Post Count: 3108 Status: Offline Project Badges: 
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If you talk about that seti link, which then goes nowhere, nothing new about the bacterium plant on the aegis mosquito.[ot]Pity you don't crunch any more, [/ot] some have requested...here it is: - http://www.smh.com.au/national/zika-virus-aus...tion-20160203-gmkpx3.html - http://www.abc.net.au/am/content/2016/s4409628.htm  |
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Jim1348
Veteran Cruncher USA Joined: Jul 13, 2009 Post Count: 1066 Status: Offline Project Badges:
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I have often wondered why WCG never had a project to search for macromolecules to control diseases (it may be a modeling software limitation). I believe there is one medicine for HIV that uses macromolecules. I hope they have not put an unnecessary limitation in to protect us. I have lots of memory to spare on all my machines. They could segregate the tasks into small ones and large ones if necessary. |
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robertmiles
Senior Cruncher US Joined: Apr 16, 2008 Post Count: 443 Status: Offline Project Badges:
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One of the current limitations in projects run on WCG is using libraries of small molecules (<600 molecular weight, I believe) to try to interact with the disease-causing organisms. In May, IBM announced the discovery of a new macromolecule (large molecule) that may be effective against Zika, Ebola, and Dengue Fever. I have often wondered why WCG never had a project to search for macromolecules to control diseases (it may be a modeling software limitation). I believe there is one medicine for HIV that uses macromolecules. Anyway, before I go off into the "verbose mode", IBM's announcement may be accessed at http://www.ibn.a-star.edu.sg/images/cms_press/press_121.pdf I've seen some BOINC projects avoid macromolecules because the time to run the workunits goes up much faster than the molecular weight - for example, at least four times as long for twice the molecular weight. However, IBM's announcement looks like they found three separate small molecules that attack the diseases in separate ways, then found a way to combine the three into a macromolecule with all three parts still active. This would mean that if a disease started developing resistance to one of the parts, the other two would probably kill it before much multiplication. |
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Richard Mitnick
Veteran Cruncher USA Joined: Feb 28, 2007 Post Count: 583 Status: Offline Project Badges:
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Here is an article today in Science Alert about a vaccine going into clinical trials:
----------------------------------------https://sciencesprings.wordpress.com/2016/06/...trials-of-a-zika-vaccine/ |
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Jim Slade
Veteran Cruncher Joined: Apr 27, 2007 Post Count: 664 Status: Offline Project Badges:
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Scientists have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication. This work reveals new leads that may be useful for halting Zika, dengue and other emerging viral infections.
http://www.sciencedaily.com/releases/2016/06/160621132534.htm  |
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[VENETO] boboviz
Senior Cruncher Joined: Aug 17, 2008 Post Count: 183 Status: Offline Project Badges: 
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I have often wondered why WCG never had a project to search for macromolecules to control diseases (it may be a modeling software limitation). I believe there is one medicine for HIV that uses macromolecules. Large simulations request high parallelism and high IPC's cpus (Xeon or Opteron) not to have too long wus. Solutions? - Multithreaded wus - Gpu wus |
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