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Category: Completed Research
Forum: Help Conquer Cancer
Thread: Interesting News Articles About Cancer |
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Thread Status: Active Total posts in this thread: 954
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
A Computational Model of an Anticancer Nanoparticle
MIT's Technology Review reports IBM's Blue Gene supercomputer has uncovered a novel drug interaction site. http://www.technologyreview.com/news/429098/a...l-model-of-an-anticancer/ |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Not a very sciency write up [The Telegraph style], but interesting [and dangerous at same time] in concept.
A virus that kills cancer: the cure that's waiting in the cold If such a gene manipulated virus goes rough, "I Am Legend" for real, is the risk. |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges: 
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http://www.medicalnewstoday.com/releases/247366.php
"Article Date: 04 Jul 2012 The Surprising Answer To Why Cancer Rate Increases With Age Cancers are age-related, much more frequent in the old than in the young. A University of Colorado Cancer Center review published in the journal Oncogene argues against the conventional wisdom that the accumulation of cancer-causing mutations leads to more cancer in older people, instead positing that it is the changing features of tissue in old age that promote higher cancer rates in the elderly. "If you look at Mick Jagger in 1960 compared to Mick Jagger today, it's obvious that his tissue landscape has changed," says James DeGregori, PhD, investigator at the University of Colorado Cancer Center and professor of molecular biology at the University of Colorado School of Medicine. "And it's this change, not the accumulation of cancer-causing mutations, that drives cancer rates higher as we grow older..." |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges:
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http://www.medicalnewstoday.com/releases/247403.php
"Article Date: 05 Jul 2012 Risk Of Bladder Cancer May Increase With Some Diabetes Drugs An increased risk of bladder cancer is linked to the use of pioglitazone, a medication commonly used to treat type 2 diabetes, according to a new study published in CMAJ (Canadian Medical Association Journal). People with type 2 diabetes are at risk of several types of cancer, including a 40% increased risk of bladder cancer, compared to people without diabetes. Previous studies have shown a higher incidence of bladder cancer in people taking pioglitazone, a type of thiazolidinedione..." |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges:
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http://www.medicalnewstoday.com/releases/247444.php
"Article Date: 05 Jul 2012 'Magic-Bullet' Cancer Therapy To Be Investigated Scientists at the University of Sheffield will investigate a new 'magic-bullet' cancer therapy that exploits tumour cells' greed for fat following an award from Yorkshire Cancer Research. Higher rates of the most deadly cancers, such as colorectal and breast cancer, have been linked to obesity or high fat diets because cancer cells use fat to grow larger and more dangerous. They are able to uptake fat by producing large amounts of structures on their surfaces called receptors, which allow chemicals to bind with the cell. Dr Irene Canton, of the university's Department of Biomedical Science, plans to produce smart nanoparticles that are uptaken by two of the main receptors, known as SR-B1 and CD36. These nanoparticles could then be used to carry therapies directly to the cancer cells, without affecting healthy cells..." |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges:
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http://www.medicalnewstoday.com/articles/247497.php
"Article Date: 05 Jul 2012 Oral Cancer Virus Associated With Gum Disease After the discovery that severe gum disease can be associated with a higher risk of head and neck cancer cases caused by the Human Pailloma Virus (HPV), The British Dental Health Foundation aims to educate the public on good oral health. Researchers discovered that in comparison with patients with HPV-negative tumors, those with HPV-positive tumors had a considerably higher bone loss, which is a key element for developing severe gum disease. According to the latest figures, over 6,000 people in the UK have oral cancer, a disease that claims nearly 2,000 lives. The incident rates of oral cancer due to HPV are increasing, with experts indicating that within a decade, HPV may rival tobacco use as the main cause for oral cancer. Other risk factors for oral cancer include smoking, excessive drinking and poor diet. The importance of the research is even more significant as it also shows that more teeth are lost through periodontal (gum) disease than through tooth decay. In a study, published in the Archives of Otolaryngology, the researchers examined 124 patients with oral cancer and discovered that the cancer in 50 patients was a result of HPV. Lead researcher Mine Tezal, D.D.S., Ph.D., of the University at Buffalo said: "Periodontitis is easy to detect and may represent a clinical high-risk profile for oral HPV infection." This is not the first time that poor oral health and cancer have been associated with each other. However, further research is needed to determine the precise relationship between the link of severe gum disease and a higher risk of HPV-related oral cancer. According to a recent study at the Karolinska Institute in Sweden, failing to clean your teeth properly could raise the risk of premature death due to cancer. The Swedish team discovered that high levels of dental plaque, which causes gum disease, and cancer mortality can result in an up to 13-year earlier premature death..." |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges:
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http://www.medicalnewstoday.com/articles/247503.php
"Article Date: 06 Jul 2012 Combination Therapy For Breast Cancer Shows Promise A study published in the July issue of Anticancer Research reveals that scientists from Boston University School of Medicine (BUSM) have found an effective combination therapy for breast cancer cells in vitro that can potentially be used for treating different forms of breast cancer, including cancers resistant to chemotherapy as well as other treatments. The Centers for Disease Control and Prevention state that aside from non-melanoma skin cancer, breast cancer is the most common form of cancer amongst women in the U.S., and it is also one of the top mortality causes in women of all races. About 14 to 20% of all breast cancer cases are triple negative breast cancer, meaning the cancer cells lack hormone receptors, including the HER-2 receptor, and are generally unresponsive to hormone and herceptin-based therapies. Triple negative breast cancer is a more aggressive cancer with higher recurrence and mortality rates than other types of breast cancer. This type of cancer is more prevalent in African-American women. Study author Sibaji Sarkar, PhD, adjunct instructor of medicine at BUSM explains: "Cancer is like a car without brakes. Cell growth speeds up and it doesn't stop. When expressed, tumor suppressor genes, which work in a protective way to limit tumor growth, function as the brakes. They are not expressed in most cancers, causing the cancer to grow and potentially metastasize." The main aim in the development of anti-cancer drugs is to find a method to re-express tumor suppressor genes that can help to block the growth of cancer cells. Whilst some tumor suppressor genes are imprinted, i.e. only one of the genes inherited from the mother and father is functional, in those with cancer, both imprinted tumor suppressor genes can become non-functional and unable to stop tumor growth. The researchers conducted an in vitro study to test a combination therapy of an epigenetic drug combined with a protease inhibitor on breast cancer cell lines that are hormone responsive and on those, i.e. the triple negative that are hormone unresponsive. They used histone deacetylases inhibitors (HDACi) and calpeptin. Calpeptin blocks the protein calpain, which is involved in controlling signaling proteins and which is currently being researched as a potential treatment model for blood clots and other neurological diseases..." |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges:
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http://www.medicalnewstoday.com/releases/247509.php
"Article Date: 06 Jul 2012 Identification Of Critical 'Quality Control' For Cell Growth Has Implications For The Development Of New Anti-Cancer Drugs Scientists from the Florida campus of The Scripps Research Institute have identified a series of intricate biochemical steps that lead to the successful production of proteins, the basic working units of any cell. The study, which appears in the journal Cell, sheds light on the assembly of a structure called the ribosome, a large and complex protein-producing machine inside all living cells. Ribosomes are the targets of many commercially used antibiotics and represent a promising area of research because of the importance of ribosome assembly and function for cell growth. There are well-established links between defects in ribosome assembly and cancer, making this pathway a potential new target for anti-cancer drugs..." |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges:
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http://www.medicalnewstoday.com/releases/247552.php
"Article Date: 09 Jul 2012 Molecule Discovered That Starves Lung Cancer And Improves Ventilator Recovery A new research report published online in the FASEB Journal reveals a connection among sugar, cancer, and dependence on breathing machines - microRNA-320a. In the report, Stanford scientists show that the molecule microRNA-320a is responsible for helping control glycolysis. Glycolysis is the process of converting sugar into energy, which fuels the growth of some cancers, and contributes to the wasting of unused muscles such as the diaphragm when people are using ventilators. Identifying ways to use microRNA-320a to starve tumors and keep unused muscles strong would represent a significant therapeutic leap for numerous diseases and health conditions..." |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges:
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http://www.medicalnewstoday.com/releases/247560.php
"Article Date: 09 Jul 2012 Prostate cancer doesn't kill in the prostate - it's the disease's metastasis to other tissues that can be fatal. A University of Colorado Cancer Center study published this week in the Journal of Biological Chemistry shows that prostate cancer cells containing the protein SPDEF continue to grow at the same pace as their SPDEF- cousins, but that these SPDEF+ cells are unable to survive at possible sites of metastasis. "It's as if these cancer cells with SPDEF can't chew into distant tissue and so are unable to make new homes," says Hari Koul, PhD, investigator at the CU Cancer Center and director of urology research at the University of Colorado School of Medicine, the study's senior author..." |
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