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fredriley
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REQ: DNA and RNA vector images

Hi

This is probably a strange forum to post this request in, but I couldn't see anywhere suitable - if there is a better forum, please point me towards it. Anyway, I've at last got BOINC running WCG projects on my work machine, and came back from making tea just now to find some very nice protein images on my screen. Where I work at the University of Nottingham we develop Reusable Learning Objects for Nursing education, which are basically bite-sized chunks of e-learning (see www.nottingham.ac.uk/nursing/sonet/rlos/). An object we currently have under development needs some vector images of DNA and mRNA to illustrate the role of hydrogen bonding in the synthesis of these molecules in organisms, but I've hunted far and wide for such images and not come across any. Would anyone at WCG or its participating projects be willing to let us have suitable images? Strictly non-commercial educational purposes only.

Perhaps a cheeky request, but as my mum always said, if you don't ask, you dont' get ;-)

Cheers

Fred
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Re: REQ: DNA and RNA vector images

Hi fredriley,
I don't know how we do it, but how do you like the images put out by Rosetta@home?
http://boinc.bakerlab.org/rosetta/rah_top_predictions.php
Lawrence
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fredriley
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Re: REQ: DNA and RNA vector images

Hi fredriley,
I don't know how we do it, but how do you like the images put out by Rosetta@home?
http://boinc.bakerlab.org/rosetta/rah_top_predictions.php
Lawrence


Good stuff, Lawrence, though not what we're after. We want to illustrate the way DNA and mRNA 'zips up' along the bases. What I've got in mind (and I'm no biologist, mind) is a classic DNA image with bases connected by 'rungs', whch we can break up into two 'half-ladders' then stitch together again. We might have to draw our own, but it would certainly save a lot of time if we could find something 'ready-rolled', as it were.

Cheers

Fred
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Sekerob
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Re: REQ: DNA and RNA vector images

The origins of life... a bit older than 10,000 years: http://universe-review.ca/F11-monocell.htm

From the publication:
The gene-censoring mechanism is thought to have emerged about a billion years ago to protect some common ancestor to plants, animals and fungi against viruses and mobile genetic elements. RNAi appears to work like this (as shown in Figure 11-26a): Inside a cell, double-stranded RNA encounters an enzyme dubbed Dicer. Using the chemical process of hydrolysis, Dicer cleaves the long RNA into pieces, known as short interfering RNAs, or siRNAs. Each siRNA is about 22 nucleotides long. The siRNA duplex is then unwound, and one strand of the duplex is loaded into an assembly of proteins to form the RNA-induced silencing complex (RISC).

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fredriley
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Re: REQ: DNA and RNA vector images

The origins of life... a bit older than 10,000 years: http://universe-review.ca/F11-monocell.htm


Thanks for the pointer - the DNA diagrams at http://universe-review.ca/F11-monocell.htm#DNA are just what we're after, but we really need them in vector, not bitmap, form, as we want to manipulate and animate them, such as showing the two halves zipping together. We could I suppose use bitmaps but it would look pretty clunky IMO, and we wouldn't be able to pull the helix apart then reassemble it.

We might have to get hold of a protein modelling application and generate the images from scratch, but as noted I'm no biologist so wouldn't know where to start. PovChem might be another option. I'd like to avoid learning these applications just to produce a couple of images, though, if I can.

Cheers

Fred
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