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alged
Master Cruncher FRANCE Joined: Jun 12, 2009 Post Count: 2360 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
doing an apple a day, instead of eating a 7 of them on Sunday - tactics! ![]() that works well to fight bad cholesterol ![]() ![]() |
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alged
Master Cruncher FRANCE Joined: Jun 12, 2009 Post Count: 2360 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Cancer markers are showing their accuracy and efficiency to detect lung cancer. Read what french doctors and scientists aim to
----------------------------------------from the paper Nice-Matin --- Un test sanguin pour détecter le cancer du poumon mis au point à Nice Publié le vendredi 31 octobre 2014 à 19h00 C'est une première mondiale. Une équipe nicoise a mis au point un test sanguin permettant la détection d'un cancer du poumon, avant mème qu'il soit visible en imagerie. C'est un immense pas dans la médecine moderne qui vient d'être accompli par le Pr Paul Hofman du CHU de Nice et son équipe (1). Ils viennent en effet de montrer comment le cancer du poumon peut être diagnostiqué des mois, voire des années, avant sa détection par scanner. 245 patients suivis L'étude a consisté à suivre pendant cinq années (2008 à 2013) un groupe de 245 patients niçois et nancéens, dont 168 présentaient un risque élevé de développer un cancer du poumon car fortement tabagiques et atteints de Bronchopathie Chronique Obstructive (BPCO). Chez cinq de ces patients, des cellules tumorales étaient mises en évidence dès 2008, grâce à un simple test sanguin, alors que l'imagerie par scanner ne mettait en évidence aucune tumeur au niveau pulmonaire. Un à quatre ans plus tard, chez les cinq patients, un nodule est devenu détectable, et tous ont été immédiatement opérés. Un an après cette chirurgie, réalisée très précocement, aucun signe de récidive n'était observé. Un brevet américain déposé Cette étude préliminaire, qui a fait l'objet d'un dépôt de brevet américain, doit à présent être vérifiée à plus large échelle. Des levées de fonds européens sont prévues, qui permettront de réaliser un essai sur quelques 5000 patients. Rappelons que le cancer du poumon est parmi les plus meurtriers; la survie des patients, diagnostiqués le plus souvent tardivement, est de seulement 16% à 5 ans. Seulement 15% de ces cancers sont actuellement dépistés à un stade de maladie localisée. Donc opérables. --------- from the paper Nice-Matin Des scientifiques niçois sur la piste d'un "traitement miracle" contre le cancer Publié le mardi 16 décembre 2014 à 13h55 - -- Les chercheurs niçois sont décidemment à la pointe de la lutte contre le cancer. Après la découverte du Pr Paul Hofman d'un test sanguin pour détecter le cancer, une autre équipe de chercheurs et médecins de Nice est sur la piste d'un traitement miracle contre cette terrible maladie. Un médicament capable à la fois d'empécher la tumeur de se développer, mais aussi de faire des ramifications: grâceà Nicole Wagner, Kay-Dietrich Wagner et Jean-François Michiels, des chercheurs et médecin niçois, cet espoir thérapeutique devient tangible. "Ce qui est extraordinaire, c'est qu'une immunothérapie efficace et sans effets indésirables est déjà en essai clinique au Japon, en Italie, et en Allemagne", s'enthousiasme Nicole Wagner. Les premiers résultats sont très encourageants et ces études sont publiées ce mardi dans l'excellente revue Nature Communications. ---- ![]() |
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l_mckeon
Senior Cruncher Joined: Oct 20, 2007 Post Count: 439 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Drug combination produces long-term responses in patients with mantle cell lymphoma (Rare form of non-Hodgkin's Lymphoma)
New research from Moffitt Cancer Center and its collaborators find that the drug combination rituximab plus lenalidomide was effective and produced long-term responses in patients with mantle cell lymphoma. The results from the multicenter phase 2 study were published in the Nov. 5 issue of The New England Journal of Medicine. [. . .] The combination of lenalidomide and rituximab was very effective in previously untreated mantle cell lymphoma patients. Ninety-two percent of patients who could be evaluated had either a complete response or a partial response to therapy, with 64 percent of patients achieving a complete response. [. . .] The responses to treatment were also durable. Eighty-five percent of patients were alive two years after therapy without experiencing any disease progression. Etc. Australian researchers think the treatment may be applicable to other blood cancers. http://www.news-medical.net/news/20151113/Dru...mantle-cell-lymphoma.aspx |
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Jim1348
Veteran Cruncher USA Joined: Jul 13, 2009 Post Count: 1066 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
It May Soon Be Possible to Screen for Ovarian Cancer
There is no reliable way to detect ovarian cancer, which may explain why most women who are diagnosed already have advanced disease. But this test may change that http://time.com/4152550/ovarian-cancer-screening/ |
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l_mckeon
Senior Cruncher Joined: Oct 20, 2007 Post Count: 439 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Modified fat cells allow imaging of glioma cell brain tumors.
Researchers at Penn State College of Medicine are claiming to have found an early route through the blood-brain barrier. They have developed a new type of fat cell that contains a commonly used contrast agent called Magnevist, and embedded on its surface proteins that target receptors on glioma cells. The researchers found that the engineered fat cell was able to penetrate the blood-brain barrier in mice and seek out early stage tumors. http://www.gizmag.com/fat-cells-blood-brain-tumor/40974/ |
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l_mckeon
Senior Cruncher Joined: Oct 20, 2007 Post Count: 439 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Australian researchers identify a protein which can cause breast cancer to worsen or spread.
The protein drives milk production in pregnancy but a new study has shown it can also cause the spread of breast cancer. The researchers hope this discovery will lead to more effective treatments. Dr David Gallego-Ortega from the Garvan Institute of Medical Research co-led the study and is speaking here with Sarah Sedghi. "So we have identified a protein which is called Elf5 that goes rogue in breast cancer. Now, Elf5 produces inflammation and then tricks the immune system, which has the inflammatory cells, into helping them to, helping the cancer cells to metastasize which is the spread throughout the body. And this is, metastasis is the actual biggest killer in breast cancer." Etc. Another interview said they're going to try existing anti-inflammatory drugs as a treatment, as it's the localized inflammation that makes the blood vessels leaky and allows the cancer cells to get into the blood stream. http://www.abc.net.au/news/2015-12-31/austral...protein-which-can/7061244 Note the transcript button. |
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l_mckeon
Senior Cruncher Joined: Oct 20, 2007 Post Count: 439 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Sugar (esp. fructose) Might Fuel the Growth of Cancer
Researchers may be able to explain how sugar might fuel the growth of cancer. They say it boils down to one type of sugar in particular: fructose [also sucrose]. Tests in mice show a possible mechanism for how it happens. The findings, published in the journal Cancer Research, support studies that suggest people who consume more sugar have a higher risk of cancer — especially breast cancer [and lung cancer]. Etc. http://www.nbcnews.com/health/cancer/here-s-h...uel-growth-cancer-n488456 |
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cjslman
Master Cruncher Mexico Joined: Nov 23, 2004 Post Count: 2082 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
A new cancer test is getting some serious investment from two of the richest people in the world.
----------------------------------------Bill Gates and Jeff Bezos pour millions into new cancer test CJSL Crunching like there's no tomorrow... |
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cjslman
Master Cruncher Mexico Joined: Nov 23, 2004 Post Count: 2082 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Making immune cells reliant on a "switch" molecule cuts down on their toxicity.
----------------------------------------Keeping immune cells engineered to kill cancer from killing everything else CJSL Crunching for a brighter future... |
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SekeRob
Master Cruncher Joined: Jan 7, 2013 Post Count: 2741 Status: Offline |
Scientists 'find cancer's Achilles heel': http://www.bbc.com/news/health-35718491
But, one observation is important to note: "People have tried to steer the immune system to kill tumours before, but cancer vaccines have largely flopped. One explanation is that they are training the body's own defences to go after the wrong target." Kind of like autoimmune diseases, but possibly worse. |
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