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World Community Grid Forums
Category: Active Research
Forum: OpenPandemics - COVID-19 Project
Thread: Coming Soon: OpenPandemics |
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Thread Status: Locked Total posts in this thread: 6
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jhindo
Former World Community Grid Admin Joined: Aug 25, 2009 Post Count: 250 Status: Offline Project Badges: 
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Dear Volunteers,
Today, IBM announced OpenPandemics , a new World Community Grid project in partnership with Scripps Research. Once launched, this project's main goals are:
World Community Grid has been working behind the scenes to get the project launched as quickly as possible and we'll keep you up to date throughout this process. As soon as we begin alpha testing (internal testing of work units that will eventually be sent to volunteers' computers), we will make an announcement in this thread. We'll also update this thread with links to announcements about beta testing, the project launch, and regular project updates, so that anyone visiting the forum can quickly find the latest information. In order to keep these announcements as visible as possible to all forum visitors, this thread will be locked. Volunteers are encouraged to post about OpenPandemics on the following threads:
Also, we will be strictly enforcing our communications guidelines, which you can read here . We're thankful for everyone's support for World Community Grid and all humanitarian scientific research. Now, more than ever, we're all in this together. Many thanks, Juan |
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uplinger
Former World Community Grid Tech Joined: May 23, 2005 Post Count: 3952 Status: Offline Project Badges: 
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Hello,
I want to update everyone that we have started Alpha testing against the actual COVID-19 target. We have a sample set of small ligands to compare against COVID-19. This Alpha testing is on devices that are owned by members of the World Community Grid team. We are doing this to help give us an idea if the binaries work well and the work units do not crash. So far things are looking well as we work through issues. Alpha testing will hopefully be short, but one of the things we are testing is work unit sizing as different ligands take different times to complete, sometimes exponentially. We are getting a larger subset of ligands to test on Alpha later today to help with the sizing problem. Thanks again for your interest and look forward to a BETA soon :P -Uplinger |
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seippel
Former World Community Grid Tech Joined: Apr 16, 2009 Post Count: 392 Status: Offline Project Badges: 
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Hello everyone,
We've been working on the screensaver for OpenPandemics. There may be additional changes before launch, but we thought we would share how it looks so far for anyone interested:  Seippel |
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jhindo
Former World Community Grid Admin Joined: Aug 25, 2009 Post Count: 250 Status: Offline Project Badges:
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Hi everyone,
A quick update: we just started an initial Beta test. For now, we’re using manually created work units, which are actually targeting a protein in the virus. The aim of this initial beta run is to test the science application (AutoDock), results validation and work unit sizing. The initial validation will be with redundancy (where we send out two copies of each work unit), which will help us confirm the validator works against all CPU types within the same operating system. However, at launch, this project should run similarly to other previous AutoDock-based World Community Grid projects - i.e. besides random comparison checks, work units will run with no comparison/redundancy. In the meantime, we are testing the automation of work unit generation on our Alpha environment and once those tests are complete, we’ll proceed with automatic work unit generation on beta. For the latest on this beta test, please visit this issues thread: https://www.worldcommunitygrid.org/forums/wcg/viewthread_thread,42310 If you’d like to participate in this test, make sure you’re signed up for beta testing here: https://www.worldcommunitygrid.org/ms/device/viewBetaProfiles.do . Many thanks for your continued interest in OpenPandemics, Juan |
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jhindo
Former World Community Grid Admin Joined: Aug 25, 2009 Post Count: 250 Status: Offline Project Badges:
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Hi everyone,
While we continue with beta testing, we wanted to clarify some details about the project approach. The primary goal of OpenPandemics is to search for potential treatments for COVID-19, so studying proteins from SARS-CoV2 (the virus that causes COVID-19) is the highest priority. Additionally, scientists want to fight not only the current emergency, but also prepare for the ones that will likely follow. Future pandemics could stem from a progressive accumulation of mutations, which can eventually lead to a new virus variant. This is what happened when the virus SARS-CoV1 mutated to become SARS-CoV2. So the research team will also include proteins from the SARS-CoV1 to be studied as part of OpenPandemics, which will help them assess how difficult would it be to find or design molecules capable of overcoming the inevitable mutations. Many thanks, Juan |
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jhindo
Former World Community Grid Admin Joined: Aug 25, 2009 Post Count: 250 Status: Offline Project Badges:
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Hi everyone,
The OpenPandemics project is now live! You can see the announcement here . Many thanks for your support, Juan |
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