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Re: Interesting news articles about AIDS

'Gold' Fish Thrive, Cancers Die
http://www.sciencedaily.com/releases/2010/09/100927155326.htm

it seems to me that this can be also a solution to "latent reservoirs"
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Michael2901
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Re: Interesting news articles about AIDS

Not seen very many new posts recently, so I am posting some more articles hoping to encourage more posts by others....

http://www.amfar.org/lab/article.aspx?id=9028 "Gene Therapy and the Potential for an HIV Cure September 10, 2010— Three years ago, an HIV patient in Berlin requiring treatment for leukemia received a stem cell transplant and the results changed the AIDS research world. Preparing for the procedure, his doctors searched for a donor who was not only a tissue match but also had a rare genetic mutation called CCR5 delta-32, which blocks HIV infection in almost all cases. Since the transplant, the patient has stopped taking antiretroviral therapy and no HIV has been detected in his body. He appears to have been the only person ever cured of HIV...."
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Michael2901
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Re: Interesting news articles about AIDS

http://www.elements4health.com/possible-metho...-infants-against-hiv.html
"Possible Method for Protecting Infants Against HIV 04 October 2010..... Researchers may have uncovered a new weapon for combating HIV as it is passed from mother to newborn child..."
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Michael2901
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Re: Interesting news articles about AIDS

Some useful effort from governments...

http://www.medicalnewstoday.com/articles/203514.php
"Main Category: HIV / AIDS
Article Date: 05 Oct 2010 - 5:00 PDT

African Leaders To Meet In Zambia To Discuss Country Responses To HIV/AIDS

Later this month, "[f]our former heads of state and other high-level African leaders who are the champions for a HIV/AIDS-free generation project" will travel to Zambia at the request of Zambian President Rupiah Banda for a meeting to discuss ways to strengthen the HIV/AIDS response in Africa...."

http://www.medicalnewstoday.com/articles/203656.php
"Main Category: HIV / AIDS
Article Date: 06 Oct 2010

Obama Administration Expected To Announce $4B Pledge To Global Fund

The Obama administration is expected on Tuesday to announce a large increase in its pledge to the Global Fund to Fight AIDS....."
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Michael2901
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Re: Interesting news articles about AIDS

http://www.sciencedaily.com/releases/2010/10/...3A+Latest+Science+News%29

"ScienceDaily (Oct. 6, 2010)

New Computer Modelling System Predicts Responses to HIV and AIDS Treatments

A new system for predicting how individual patients with HIV and AIDS will respond to different drugs is launched October 6 by RDI, a UK-based not-for-profit research group. The experimental system, called the HIV Treatment Response Prediction System (HIV-TRePS), is available free of charge over the Internet and helps physicians select the best treatment for their patients....."
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Michael2901
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Re: Interesting news articles about AIDS

http://www.physorg.com/news205686301.html

October 7, 2010

"Researchers target HIV-related brain difficulties
During the last two decades, scientists and doctors have developed a potent mix of medications that nearly stops HIV in its tracks for most patients....

But that success does not extend fully to the brain, where an assault triggered by the virus continues despite treatment. About half of patients infected by HIV experience symptoms, such as difficulty thinking or concentrating, as a result of the effects of the virus on the brain. So far, nearly a dozen studies in people have failed to identify a drug useful for treating the condition, which is known as HIV-associated neurocognitive disorder..."
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Michael2901
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Re: Interesting news articles about AIDS

http://www.medicalnewstoday.com/articles/204002.php

More anti-HIV research lead by Scripps Research Institute who are behind the WCG non-profit Fight Against AIDS project

October 9, 2010

"First Structure Of A Class Of Proteins That Help Guide Blood Cell Movement Revealed: Findings May Lead To New Drugs For Cancer, Immune Disorders Aids

Researchers have determined the structure of a protein that helps guide blood-forming stem cells, or hematopoetic stem cells. The protein is also one of the main receptors used by the human immunodeficiency virus (HIV) to get inside blood cells.

The findings are described in the journal Science.

The structure offers a detailed view of how the cell surface receptor, called CXCR4, interacts with molecules outside the cell. The results have implications for developing new drugs for hematopoetic stem cell transplantation, a therapeutic path to treat cancer and immune disorders, as well as for treating HIV infection.

"The structures open up entire new areas for understanding fundamental principles in chemokine GPCR signaling," said Scripps Research Professor Raymond C. Stevens, who is senior author of the collaborative study...."
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Re: Interesting news articles about AIDS

Conventional Theory of Modern Drug Design Challenged

http://www.sciencedaily.com/releases/2010/10/101010133612.htm

as protein receptors change shape ligands can adapt to that change, binding productively to both active and inactive structures.

To our great surprise, the ligand bound differently to the active and inactive conformations of the receptor," said Kendall Nettles, an associate professor in the Department of Cancer Biology at Scripps Florida. "This strongly suggests a novel mechanism for managing [cell] signaling activity. The implications of this are profound, both for our understanding of how ligands regulate protein activity, and as a novel approach in drug discovery
[Oct 11, 2010 9:44:33 AM]   Link   Report threatening or abusive post: please login first  Go to top 
Michael2901
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Re: Interesting news articles about AIDS

http://www.sciencedaily.com/releases/2010/05/...3A+Latest+Science+News%29

"ScienceDaily (Oct. 11, 2010) ” A cell small in number but powerful in its ability to switch the immune system on or off is a unique hybrid of two well-known immune cell types, Medical College of Georgia researchers report...."
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Michael2901
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Re: Interesting news articles about AIDS

http://www.medicalnewstoday.com/articles/204109.php

"Financing HIV/AIDS Prevention, Treatment Could Cost $400B-$700B Over 20 Years

Main Category: HIV / AIDS
Also Included In: Preventive Medicine
Article Date: 11 Oct 2010 - 1:00 PDT

A new report published by the Results for Development Institute in the Lancet "has offered governments and donors a glimpse into the future of HIV epidemics - and what it will cost to prevent and treat them. Researchers warn of hard choices ahead and a need for some countries to take more responsibility for their national programmes," IRIN/PlusNews reports. Study authors present their "cheapest" and "ideal" scenarios for HIV/AIDS funding in the future, according to IRIN/PlusNews.

"One of the surprising things we found was that the price tag [to fund HIV programmes] could vary so significantly from as relatively little as around $400 billion to as much as about $700 billion," said study author Robert Hecht, managing director of Results for Development..."
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