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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
'Gold' Fish Thrive, Cancers Die
http://www.sciencedaily.com/releases/2010/09/100927155326.htm it seems to me that this can be also a solution to "latent reservoirs" |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Not seen very many new posts recently, so I am posting some more articles hoping to encourage more posts by others....
http://www.amfar.org/lab/article.aspx?id=9028 "Gene Therapy and the Potential for an HIV Cure September 10, 2010— Three years ago, an HIV patient in Berlin requiring treatment for leukemia received a stem cell transplant and the results changed the AIDS research world. Preparing for the procedure, his doctors searched for a donor who was not only a tissue match but also had a rare genetic mutation called CCR5 delta-32, which blocks HIV infection in almost all cases. Since the transplant, the patient has stopped taking antiretroviral therapy and no HIV has been detected in his body. He appears to have been the only person ever cured of HIV...." |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
http://www.elements4health.com/possible-metho...-infants-against-hiv.html
"Possible Method for Protecting Infants Against HIV 04 October 2010..... Researchers may have uncovered a new weapon for combating HIV as it is passed from mother to newborn child..." |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Some useful effort from governments...
http://www.medicalnewstoday.com/articles/203514.php "Main Category: HIV / AIDS Article Date: 05 Oct 2010 - 5:00 PDT African Leaders To Meet In Zambia To Discuss Country Responses To HIV/AIDS Later this month, "[f]our former heads of state and other high-level African leaders who are the champions for a HIV/AIDS-free generation project" will travel to Zambia at the request of Zambian President Rupiah Banda for a meeting to discuss ways to strengthen the HIV/AIDS response in Africa...." http://www.medicalnewstoday.com/articles/203656.php "Main Category: HIV / AIDS Article Date: 06 Oct 2010 Obama Administration Expected To Announce $4B Pledge To Global Fund The Obama administration is expected on Tuesday to announce a large increase in its pledge to the Global Fund to Fight AIDS....." |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
http://www.sciencedaily.com/releases/2010/10/...3A+Latest+Science+News%29
"ScienceDaily (Oct. 6, 2010) New Computer Modelling System Predicts Responses to HIV and AIDS Treatments A new system for predicting how individual patients with HIV and AIDS will respond to different drugs is launched October 6 by RDI, a UK-based not-for-profit research group. The experimental system, called the HIV Treatment Response Prediction System (HIV-TRePS), is available free of charge over the Internet and helps physicians select the best treatment for their patients....." |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
http://www.physorg.com/news205686301.html
October 7, 2010 "Researchers target HIV-related brain difficulties During the last two decades, scientists and doctors have developed a potent mix of medications that nearly stops HIV in its tracks for most patients.... But that success does not extend fully to the brain, where an assault triggered by the virus continues despite treatment. About half of patients infected by HIV experience symptoms, such as difficulty thinking or concentrating, as a result of the effects of the virus on the brain. So far, nearly a dozen studies in people have failed to identify a drug useful for treating the condition, which is known as HIV-associated neurocognitive disorder..." |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
http://www.medicalnewstoday.com/articles/204002.php
More anti-HIV research lead by Scripps Research Institute who are behind the WCG non-profit Fight Against AIDS project October 9, 2010 "First Structure Of A Class Of Proteins That Help Guide Blood Cell Movement Revealed: Findings May Lead To New Drugs For Cancer, Immune Disorders Aids Researchers have determined the structure of a protein that helps guide blood-forming stem cells, or hematopoetic stem cells. The protein is also one of the main receptors used by the human immunodeficiency virus (HIV) to get inside blood cells. The findings are described in the journal Science. The structure offers a detailed view of how the cell surface receptor, called CXCR4, interacts with molecules outside the cell. The results have implications for developing new drugs for hematopoetic stem cell transplantation, a therapeutic path to treat cancer and immune disorders, as well as for treating HIV infection. "The structures open up entire new areas for understanding fundamental principles in chemokine GPCR signaling," said Scripps Research Professor Raymond C. Stevens, who is senior author of the collaborative study...." |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Conventional Theory of Modern Drug Design Challenged
http://www.sciencedaily.com/releases/2010/10/101010133612.htm as protein receptors change shape ligands can adapt to that change, binding productively to both active and inactive structures. To our great surprise, the ligand bound differently to the active and inactive conformations of the receptor," said Kendall Nettles, an associate professor in the Department of Cancer Biology at Scripps Florida. "This strongly suggests a novel mechanism for managing [cell] signaling activity. The implications of this are profound, both for our understanding of how ligands regulate protein activity, and as a novel approach in drug discovery |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
http://www.sciencedaily.com/releases/2010/05/...3A+Latest+Science+News%29
"ScienceDaily (Oct. 11, 2010) A cell small in number but powerful in its ability to switch the immune system on or off is a unique hybrid of two well-known immune cell types, Medical College of Georgia researchers report...." |
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Michael2901
Veteran Cruncher Joined: Feb 6, 2009 Post Count: 586 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
http://www.medicalnewstoday.com/articles/204109.php
"Financing HIV/AIDS Prevention, Treatment Could Cost $400B-$700B Over 20 Years Main Category: HIV / AIDS Also Included In: Preventive Medicine Article Date: 11 Oct 2010 - 1:00 PDT A new report published by the Results for Development Institute in the Lancet "has offered governments and donors a glimpse into the future of HIV epidemics - and what it will cost to prevent and treat them. Researchers warn of hard choices ahead and a need for some countries to take more responsibility for their national programmes," IRIN/PlusNews reports. Study authors present their "cheapest" and "ideal" scenarios for HIV/AIDS funding in the future, according to IRIN/PlusNews. "One of the surprising things we found was that the price tag [to fund HIV programmes] could vary so significantly from as relatively little as around $400 billion to as much as about $700 billion," said study author Robert Hecht, managing director of Results for Development..." |
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