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World Community Grid Forums
Category: Completed Research
Forum: Human Proteome Folding
Thread: Diabetes |
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Thread Status: Active Total posts in this thread: 10
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dragokatzov
Cruncher Joined: Nov 6, 2005 Post Count: 3 Status: Offline Project Badges: 
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Is it possible that the Human Proteome Folding Project could lead to a possible cure, and/or better treatment for Diabetes? Thank you
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Hi,
Yes it is indeed possible. You can check the posts here which were for the Avian Flu, but apply equally to Diabetes. http://www.worldcommunitygrid.org/forums/wcg/viewthread?thread=5295#42145 |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
I am a Type 2 Diabetes patient and have to take oral medication every day besides controlling Carb in-take and to walk 5 KMs a day. I am happy that some one is predicting cure for Diabetes through the Grid computing approach. But I doubt if they can find a cure at all for diabetes. With all the research on the subject, I feel this condition arises due to (a) no production of insulin from pancreas (b) inadequate insuling being produced from pancreas and (c) the resistance of body cells to the insulin produced. Diabetes is not due to an external virus or bacteria and hence a cure can not be found. If a 'cure' is found, the same will not be allowed to reach people because the pharma companies will lose out. Their strategy will be to get the people used to a daily dose of medicine so that their business is intact.
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dragokatzov
Cruncher Joined: Nov 6, 2005 Post Count: 3 Status: Offline Project Badges:
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compaired to all we know about the human body, and all there is to know, we do not know a lot
think big! its possible we might find an actual cure for diabetes. i'm just trying to keep an open mind |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
compaired to all we know about the human body, and all there is to know, we do not know a lot think big! its possible we might find an actual cure for diabetes. i'm just trying to keep an open mind Of course, at some point in the advancement of human technology we will find a full cure for diabetes. So long as research actually continues. The question is not, will it be possible? The question is, WHEN will it be possible. Could be a year, ten years, a century, who knows?But one day all human disease will be a thing of the past. Technology is Incredible. |
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gordoma
Veteran Cruncher Windsor, UK Joined: Jul 21, 2005 Post Count: 729 Status: Offline Project Badges: 
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My Mum has diabetes, so I would like to see this as a project for WCG.
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dragokatzov
Cruncher Joined: Nov 6, 2005 Post Count: 3 Status: Offline Project Badges:
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My Mum has diabetes, so I would like to see this as a project for WCG. My girlfriend does, so does her father. My grandmother had it, she died before I was born. Of cource, i am not JUST trying to cure disbetes, i want to help and cure everything! :) |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
I don't think it's as simple to "cure" diabetes using protein folding from wcg. if i'm right, it's generally accepted that type II diabetes has something do with your insulin receptors, not your insulin or insulin production. The structure of insulin is well known. I don't know about the insulin receptors, but even if wcg finds something out about the insulin receptors, finding a "cure" doesn't seeem to be as simple. What probably happens with type II diabetes is that your cells are so constantly exposed to insulin (too much sugar/ carbohydrates at once?) that they downregulate their insulin receptors. As a result, they're less sensitive to insulin, don't take up as much sugar, and your blood sugar levels go up. You'd have to find some way to coax the cells in your body to upregulate those insulin receptors again, and that doesn't sound quite so easy, since it probably involves several different proteins and currently unknown systems in the cell.
Avian flu is comparatively easier--fold the proteins using rosetta, decide which one you want to target, use autodock to test a bunch of chemicals, and test the potential candidates for effectiveness. For diabetes, we're not even completely sure of the mechanisms involved in it. |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
But I doubt if they can find a cure at all for diabetes. With all the research on the subject, I feel this condition arises due to (a) no production of insulin from pancreas (b) inadequate insuling being produced from pancreas and (c) the resistance of body cells to the insulin produced. Perhaps it's like you said, but doesn't everything comes from DNA and proteins that are made from DNA? I mean, pancreas cells are specialized cells that produce certain kind of chemicals, if something is wrong with proteins which constitutes that cell, it enters all the states you've mentioned. So if my layman thought are correct than it very likely in the near future to find a cure… |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
its amazing how peopel die needlesly and sufer when cures are availabel alredy for soo many diseases
----------------------------------------they probly wait for the miracle pill take one and evrthing bad goes away faster then an advil, cure and or treatment for Diabetes alredy exist folow lef protocol for complete cure for treatment and cure read and folow this protcol from lef http://www.lef.org/protocols/prtcl-042.shtml its all about beeing ahead of the game, using and knowing things that general public wiil only grasp to undestand 20years from now [Edit 2 times, last edit by Former Member at Mar 9, 2006 6:59:38 AM] |
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