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Jim Slade
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Re: Interesting News Articles About Cancer

Researchers Explore a Cancer Paradox

Healthy cells carry a surprising number of cancer-linked mutations, but they don't turn into tumors. What's holding them back?

https://www.nytimes.com/2018/10/18/science/cancer-genetic-mutations.html


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Glen David Short
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Re: Interesting News Articles About Cancer

Why tall people are more susceptible to certain cancers https://www.abc.net.au/news/science/2018-10-2...s/10404910?section=health
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KLiK
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Re: Interesting News Articles About Cancer

Why tall people are more susceptible to certain cancers https://www.abc.net.au/news/science/2018-10-2...s/10404910?section=health

Nice article, thank you. wink
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Jim Slade
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Re: Interesting News Articles About Cancer

The 10th Oxbridge varsity medical ethics debate-should we fear the rise of direct-to-consumer genetic testing?

In an increasingly data-driven age of medicine, do companies that offer genetic testing directly to patients represent an important part of personalizing care, or a dangerous threat to privacy? Should we celebrate this new mechanism of patient involvement, or fear its implications?

The Universities of Oxford and Cambridge addressed these issues in the 10th annual Medical Ethics Varsity Debate, through the motion: "This House Regrets the Rise of Direct-to-Consumer Genetic Testing." This article summaries and extends key arguments made in the debate, exploring the impacts of such genetic testing on both the individual patient and broader society, with special consideration as to whether companies can ever truly guarantee anonymity of genetic data.

https://peh-med.biomedcentral.com/articles/10.1186/s13010-018-0069-9


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Jim Slade
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Re: Interesting News Articles About Cancer

FDA clears the first consumer genetic test for how well your medications may work-with caveats

The Food and Drug Administration on Wednesday cleared the first DNA test meant to be marketed directly to consumers to help them determine how well certain drugs may work for them.

The test was developed by 23andMe and, as with other tests from the consumer genetics giant, customers will be able to simply mail in a spit sample to get results.

https://www.statnews.com/2018/10/31/fda-clear...-test-drug-effectiveness/


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Jim Slade
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Re: Interesting News Articles About Cancer

Genes have less influence on lifespan: study

A surprising new study finds genes have less control over how long people live than previously thought. The results published in the journal Genetics, discovered genes account for less than 7 percent of people's lifespan. Dr. David Agus joins "CBS This Morning" with tips for how to live longer and have a healthier life.

https://www.cbs.com/shows/cbs_this_morning/vi...usly-thought-study-finds/


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Jim Slade
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Re: Interesting News Articles About Cancer

This is a link to the article Estimates of the Heritability of Human Longevity Are Substantially Inflated due to Assortable Mating, which is in Genetics, 2018 (3):1109

https://www.sciencedaily.com/releases/2018/11/181106104247.htm


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l_mckeon
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Re: Interesting News Articles About Cancer

Obesity can both fuel tumor growth and help new immunotherapy drugs work better.

Two new studies have provided compelling insights into the relationship between obesity and cancer. The research reveals fascinatingly paradoxical effects, suggesting obesity can suppress our immune responses to enhance tumor growth, but also improve the efficacy of a new kind of cancer-killing immunotherapy.

https://newatlas.com/obesity-cancer-immune-system-checkpoint-inhibitor/57195/
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AlexGV
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Re: Interesting News Articles About Cancer

Researchers identify a mechanism that fuels cancer cells' growth

Scientists at the UCLA Jonsson Comprehensive Cancer Center have identified sodium glucose transporter 2, or SGLT2, as a mechanism that lung cancer cells can utilize to obtain glucose, which is key to their survival and promotes tumor growth. The finding provides evidence that SGLT2 may be a novel biomarker that scientists can use to help diagnose precancerous lung lesions and early-stage lung cancers.

https://medicalxpress.com/news/2018-11-mechanism-fuels-cancer-cells-growth.html
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l_mckeon
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Re: Interesting News Articles About Cancer

Scientists engineer a virus to take out cancer cells and their accomplices

Part of what makes carcinoma cells, the most common kind of cancer cell, so potent and deadly is the helping hand they receive from their neighbors. Known as cancer-associated fibroblasts, these nearby cells aid and abet the sinister machinations of the mutating cancer cells by shielding them from the body's immune system. Scientists have now developed a pioneering two-pronged virus that can target both, a new tool they describe as the first of its kind.

[. . . ]

Their experiments put the virus to work against solid prostate cancer tumor samples along with healthy bone marrow, and they found that it caused no toxicity or unwanted T-cell activation in healthy regions. And given that enadenotucirev is already undergoing trials in humans, there is hope that their modified version could also reach clinical trials as soon as next year.

https://newatlas.com/engineer-virus-cancer-cells-accomplices/57306/
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