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Thread: Interesting Medical News (Non-WCG Related Projects) |
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Thread Status: Active Total posts in this thread: 377
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twilyth
Master Cruncher US Joined: Mar 30, 2007 Post Count: 2130 Status: Offline Project Badges: 
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Telomere length related to disease susceptibility for first time
----------------------------------------This is an extraordinary example of how research into aging can produce unexpected results for medicine in general. Telomeres are repeating nucleotide sequences that cap the end of every chromosome to protect them from damage. However, every time a cell divides, a few of the nucleotides are lost and the telomere gets shorter. Eventually you reach what is called the hayflick limit and the cell enters senescence. It has long been known that people are born with telomeres of varying length and that these have implications for age-related diseases. However this is the first study to show that telomere length is also important in susceptiblity to disease even in young people. To gauge whether there was any relationship, the team conducted an experiment on 152 healthy adults, ages 18 to 55, in the Pittsburgh area. Researchers first collected blood to measure telomere length in leukocytes, or white blood cells. Then they placed the study participants in quarantine for six days, administering nasal drops containing a virus that causes the common cold (rhinovirus type 39) after the first 24 hours. More at linkOver the course of the experiment, 69% of the participants, or 105 people, were infected with the virus; 22%, or 33 people, developed colds. Overall, shorter telomeres in four types of blood cells were associated with greater risk of infection, with the strongest link occurring in a type of T-cell called CD8CD28- cells. What’s more, shorter telomere length in CD8CD28- cells was also associated with clinical illness (that is, getting a cold). The connection between shorter telomeres and infection got stronger with increasing age in study subjects. Edit: I should make it clear that this was NOT a study relating to aging, only that research into telomeres has implications for aging research - sorry, should have made that clear.   [Edit 2 times, last edit by twilyth at Mar 22, 2013 10:57:30 PM] |
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twilyth
Master Cruncher US Joined: Mar 30, 2007 Post Count: 2130 Status: Offline Project Badges:
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New IL-6 (interleukin-6) antibody could be major arthritis breakthrough
----------------------------------------The link I actually read this at is from New Scientist here but you'll need a subscription. There is already an IL-6 drug called Actemra (tocilizumab) but it is a much larger molecule and does not appear to be as effective. In one group of patients that received 3 mg per kg of body weight, the remission in symptoms was 75%. This is well higher than the 30% seen with Actemra which is based on a mammalian IL-6 antibody and considered the current "gold standard." The company, Ablynx is looking for a partner to finance a larger trial since this one was too small and short to be definitive so if you know anyone who might be interested, start checking clinicaltrials.gov in case that partner happens to be US based and they might be looking for people here. edit: oh, interesting fact, the anti-body was originally discovered in llamas and camels. [Edit 2 times, last edit by twilyth at Mar 23, 2013 7:33:05 AM] |
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alged
Master Cruncher FRANCE Joined: Jun 12, 2009 Post Count: 2360 Status: Offline Project Badges: 
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Here in France may be they have a treatment for muscular distrophy
----------------------------------------in that case of FSHD. Here the link http://sante.lefigaro.fr/actualite/2013/03/28...-contre-myopathie-ladulte Hope they will publish full results soon Cheers  |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
A 3D printed bionic ear with nanoparticles and calf cells, and it hears better than the regular ear... no more off-line wispering in that meeting with the boss: http://pubs.acs.org/doi/abs/10.1021/nl4007744...255D&searchHistoryKey
----------------------------------------[Here comes the next grid project to model the best ear for eavesdropping ;>] Edit: Here's the abstract, since one [or more], seem not to be able to reach the links destination [or register to see the full article]. A 3D Printed Bionic Ear PDF [2046 KB] PDF w/ Links[861 KB] Full Text HTML Abstract Add to ACS ChemWorx Your current credentials do not allow retrieval of the full text. Purchase the full-text Cart PDF/HTML, figures/images, references and tables, (where available) Manu S Mannoor , Ziwen Jiang , Teena James , Yong Lin Kong , Karen A Malatesta , Winston Soboyejo , Naveen Verma , David H Gracias , and Michael C. McAlpine Nano Lett., Just Accepted Manuscript DOI: 10.1021/nl4007744 Publication Date (Web): May 1, 2013 Copyright © 2013 American Chemical Society Abstract The ability to three-dimensionally interweave biological tissue with functional electronics could enable the creation of bionic organs possessing enhanced functionalities over their human counterparts. However, current electronics are inherently two dimensional, preventing seamless multidimensional integration with biology as the processes and materials used to structure synthetic tissue constructs and conventional electronic devices are very different. Here, we present a novel strategy for overcoming these difficulties via additive manufacturing of biological cells with structural and nanoparticle derived electronic elements. As a proof of concept, we generated a bionic ear via 3D printing of a cell-seeded hydrogel matrix in the precise anatomic geometry of a human ear, along with an intertwined conducting polymer consisting of infused silver nanoparticles. This allowed for the in vitro culturing of cartilage tissue around an inductive coil antenna in the ear, which subsequently connects to cochlear-like electrodes. The printed ear exhibits enhanced auditory sensing for radio frequency reception, and complementary left and right ears can listen to stereo audio music. Overall, our approach suggests a means to intricately merge biologic and nanoelectronic functionalities via 3D printing.  [Edit 1 times, last edit by Former Member at May 3, 2013 6:07:43 AM] |
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BladeD
Ace Cruncher USA Joined: Nov 17, 2004 Post Count: 28976 Status: Offline Project Badges: 
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A 3D printed bionic ear with nanoparticles and calf cells, and it hears better than the regular ear... no more off-line wispering in that meeting with the boss: http://pubs.acs.org/doi/abs/10.1021/nl4007744...255D&searchHistoryKey [Here comes the next grid project to model the best ear for eavesdropping ;>] Your current credentials do not allow retrieval of the full text. |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Researchers at the Salk Institute said all of the current Alzheimer's treatments just manage the symptoms of the disease, while this one would treat the disease itself.
http://www.nbcsandiego.com/news/local/Breakth...-Treatment-207306931.html |
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GeraldRube
Master Cruncher United States Joined: Nov 20, 2004 Post Count: 2153 Status: Offline Project Badges:
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Former Pro-GMO Scientist Speaks Out on the Real Dangers of Genetically Engineered Food
----------------------------------------By Dr. Mercola Who better to speak the truth about the risks posed by genetically modified (GM) foods than Thierry Vrain, a former research scientist for Agriculture Canada? It was Vrain’s job to address public groups and reassure them that GM crops and food were safe, a task he did with considerable knowledge and passion. But Vrain, who once touted GM crops as a technological advancement indicative of sound science and progress, has since started to acknowledge the steady flow of research coming from prestigious labs and published in high-impact journals – research showing that there is significant reason for concern about GM crops – and he has now changed his position. http://beforeitsnews.com/alternative/2013/06/...utm_source=direct-b4in.in  |
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bjbdbest
Master Cruncher Joined: May 11, 2007 Post Count: 2333 Status: Offline Project Badges: 
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To help those visually impaired:
----------------------------------------OrCam harnesses the power of Artificial Vision to compensate for lost visual abilities. A sensor that sees what is in front of you, understands what information you seek and provides it to you through a bone-conduction earpiece. Featured in the New York Times: |
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Dataman
Ace Cruncher Joined: Nov 16, 2004 Post Count: 4865 Status: Offline Project Badges: 
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US Supreme Court rules on gene patents.
----------------------------------------http://www.cnn.com/2013/06/13/politics/scotus-genes/index.html Good news for researchers and a blow to Big Pharma.   |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
silver boosts antibiotics 10x
'Collins and his team showed that when boosted with a small amount of silver these drugs could kill between 10 and 1,000 times as many bacteria. The increased membrane permeability also allows more antibiotics to enter the bacterial cells. That disruption to the cell membrane also increased the effectiveness of vancomycin, a large-molecule antibiotic, on Gram-negative bacteria which have a protective outer coating. Gram-negative bacterial cells can often be impenetrable to antibiotics made of larger molecules. http://www.scientificamerican.com/article.cfm...s-of-times-more-effective |
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