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Re: Project Status

Eternal optimism is required to think, that HIV will be eradicated! First things first is, finding ways to stop the virus replicating destroying the human resistance to common bugs turning the infection into full blown AIDS.....innoculation will be many years away, if at all.


I know it is a rather vexing problem trying to cure the AIDS scourge. What is really depressing about the workings of AIDS is that the body is fully capable of destroying the virus in its early stages of infections!

It just dosent recognize that thier is an invader in its midst because the HIV is disguised. The design of a vaccine (Yes! vaccine not treatment) is more than possible and can be done cheaply and shipped all over the world.

This can be accomplished using the Rosetta program. The same program HPF1 used and the HPF2 project coming up. The only problem here is the Rosseta program isnt yet good enough at protien structure prediction to design this Vaccine.

Aso surprising is that it is not a tech problem to get the Rosetta program at the correct level of presiction it is a computer power problem.. More and More computers are needed on the scale of at least 100,000 more processors.


Have a Nice Day alll.........Ciao
[Jun 16, 2006 12:31:38 AM]   Link   Report threatening or abusive post: please login first  Go to top 
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Re: Project Status

Now don't get pessimistic on me here.

We will find a cure/vaccine, probably in the next 10-20 years.
The future hold possibilities that we can't even imagine.

I know that HIV has a bad rep as a supervirus.
And that some people like to tag it as invinsible.

IMO there are no such thing as impossible.
HIV is a physical object and as such can be studied
and broken down in a systematic logical way.
All we need is a little patience and effort.

Chris

-- I was complaining that I had no shoes till I met a man who had no feet.
[Jun 16, 2006 5:32:55 AM]   Link   Report threatening or abusive post: please login first  Go to top 
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Re: Project Status

Source: http://www.signonsandiego.com/news/science/20060606-9999-1m6aids.html

$2.2 million machine speeds antibody search process
By Bruce Lieberman
UNION-TRIBUNE STAFF WRITER
June 6, 2006

The Scripps Research Institute Scientists hope CrystalMation will help them in the search for new HIV antibodies. In a building at The Scripps Research Institute in La Jolla, scientists are taking giant steps toward creating the world's first HIV vaccine.

[Jun 16, 2006 10:56:04 AM]   Link   Report threatening or abusive post: please login first  Go to top 
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Re: Project Status

Thanks thom217. That's an interesting article about the CrystalMation machine at Scripps Institute. I like to think our donation of CPU time made it easier for Scripps Institute to acquire the CrystalMation by freeing up funds that might otherwise have been spent on computing.
[Jun 16, 2006 3:01:39 PM]   Link   Report threatening or abusive post: please login first  Go to top 
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Re: Project Status

Dear FAAH volunteers,

The FAAH team is heading off to the National Institutes of Health next week for a meeting with other researchers working under the Structural Biology of AIDS Program. Highlighted in our presentation to this group will be the work made possible by the computational power that you have made possible. As you know, we have now been able to evaluate a large set of diverse chemical compounds against a large panel of mutant HIV protease targets. Preliminary results from the analysis of this data will be presented and discussed. The completed first stage or our computations has already provided us with important information about the data sets, and models that we use. Further investigation of the most promising compounds is currently underway. Other work under this NIH Program, including that from the Wilson and Burton labs here at Scripps will be discussed. We are all hopeful that a vaccine for HIV will be developed. In the meantime, however, we cannot forget that the current fight depends on improvement of the other two important weapons in our arsenal: public health initiatives and effective drug therapies.

On another note, the FightAIDS@Home Project and World Community was recognized last Monday by the California State Legislature with a Resolution of Commendation for the work that we are doing in the fight against AIDS. We share this honor with all of you who have joined in supporting this effort. Thank you all very much.

Art Olson
[Jun 16, 2006 7:07:11 PM]   Link   Report threatening or abusive post: please login first  Go to top 
depriens
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Re: Project Status

Thanks for the update. Good luck at the NIH and please keep us updated!
----------------------------------------

[Jun 17, 2006 7:03:51 PM]   Link   Report threatening or abusive post: please login first  Go to top 
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Re: Project Status

Dear FAAH volunteers,

The FAAH team is heading off to the National Institutes of Health next week for a meeting with other researchers working under the Structural Biology of AIDS Program. Highlighted in our presentation to this group will be the work made possible by the computational power that you have made possible. As you know, we have now been able to evaluate a large set of diverse chemical compounds against a large panel of mutant HIV protease targets. Preliminary results from the analysis of this data will be presented and discussed. The completed first stage or our computations has already provided us with important information about the data sets, and models that we use. Further investigation of the most promising compounds is currently underway. Other work under this NIH Program, including that from the Wilson and Burton labs here at Scripps will be discussed. We are all hopeful that a vaccine for HIV will be developed. In the meantime, however, we cannot forget that the current fight depends on improvement of the other two important weapons in our arsenal: public health initiatives and effective drug therapies.

On another note, the FightAIDS@Home Project and World Community was recognized last Monday by the California State Legislature with a Resolution of Commendation for the work that we are doing in the fight against AIDS. We share this honor with all of you who have joined in supporting this effort. Thank you all very much.

Art Olson
this post should be in the member news section as well as in here.
[Jun 18, 2006 6:41:32 AM]   Link   Report threatening or abusive post: please login first  Go to top 
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Re: Project Status

I work at NIH and will try to attend the lecturepresentation. Hopefully, there will be some interesting news for all of us.
[Jun 21, 2006 10:09:22 PM]   Link   Report threatening or abusive post: please login first  Go to top 
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Re: Project Status

Tangra,

I think many of us would like to hear your thoughts/impressions if you can make it to the meeting.

Halfcard,

I agree. Art Olson's post should be in the member news section. Sometimes I think WCG is just a little too humble, a little too afraid of tooting their own horn.
[Jun 21, 2006 10:34:29 PM]   Link   Report threatening or abusive post: please login first  Go to top 
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Re: Project Status

Guys, this is a message to Dr. Olson
------------------------------------------------------------------------------

Dear Dr. Olson,

Please, let me know when you will be at NIH and if your lecture/presentation will be open. I work at NIH and would definitely like to attend. However, I have not been able to find any information on your visit here.


Thank you.
[Jun 29, 2006 8:22:46 PM]   Link   Report threatening or abusive post: please login first  Go to top 
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