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World Community Grid Forums
Category: Completed Research
Forum: FightAIDS@Home
Thread: Interesting news articles about AIDS |
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Thread Status: Active Total posts in this thread: 1122
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Hi Dan60,
Dr. Perryman is no longer online, so I will tell you my (garbled) understanding of the situation. HIV belongs to a virus family that includes a variety of SIV (Simian Immune Deficiency) viruses. These viruses appear to be controlled by an anti-RNA protein secreted within each cell. Apparently (and I may be wrong) the gene is called Apobec3. It varies slightly from species to species. If an SIV virus cannot knock out the Apobec3 derived protein, then that version of SIV cannot cause a major infection in that simian species. Humans are relatively immune to most varieties of SIV, but HIV has a mutation that lets it knock out the human version of the Apobec3 derived protein, so we are vulnerable. This is just an idea I have gotten through reading various articles that I do not really understand. I may be misinforming you.  Lawrence |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
HIV rates among drug users rising
The rate of HIV infection among injecting drug users appears to be rising; researchers say... |
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Dan60
Senior Cruncher Brazil Joined: Mar 29, 2006 Post Count: 185 Status: Offline Project Badges: 
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Hi Lawrence,
----------------------------------------Thank you for considering my doubt. Yep, I've known Apobec3g protein is knocked out by HIV's Vif protein, so far. What a villain... Best regards, Dan60 P.S.: on time, "... scientists have successfully reprogrammed mature human skin cells into induced pluripotent stem (iPS) cell" ... "the iPS cells created thus far have been generated with retroviruses"... (http://www.sciencedaily.com/releases/2008/09/080910133642.htm ) Villains can help [Edit 1 times, last edit by Dan60 at Sep 25, 2008 11:35:06 PM] |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Scientists unmask key HIV protein, open door for more powerful AIDS drugs
University of Michigan scientists have provided the most detailed picture yet of a key HIV accessory protein that foils the body's normal immune response. Based on the findings, which appear online in the journal PLoS Pathogens, the team is searching for new drugs that may someday allow infected people to be cured and no longer need today's AIDS drugs for a lifetime |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
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Sekerob
Ace Cruncher Joined: Jul 24, 2005 Post Count: 20043 Status: Offline |
Colonial clue to the rise of HIV The arrival of colonial cities in sub-Saharan Africa at the dawn of the 20th Century may have sparked the spread of HIV. US experts analysed one of the earliest samples of the virus ever found, in the Democratic Republic of Congo in 1959. The study, published in the journal Nature, suggests the virus may have crossed from apes to humans between 1884 and 1924. They believe newly-built cities may have allowed the virus to thrive. continue: http://news.bbc.co.uk/2/hi/health/7646255.stm
WCG
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
What HIV Needs: Identification Of Human Facto...erapeutic Targets For HIV
The Salk Institute for Biological Studies and Burnham Institute for Medical Research today announced 295 host cell factors that are involved in human immunodeficiency virus (HIV) infection. |
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KLiK
Master Cruncher Croatia Joined: Nov 13, 2006 Post Count: 3108 Status: Offline Project Badges: 
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Hello KLiK
Seems to be the same as Sek posted above |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
3 share Nobel prize for work on AIDS and cancer
STOCKHOLM, Sweden - Three European scientists shared the 2008 Nobel Prize in medicine on Monday for separate discoveries of viruses that cause AIDS and cervical cancer, breakthroughs that helped doctors fight the deadly diseases |
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