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[CSF] Thomas Dupont
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News XXXIII

CANCER COLORECTAL : Des miARNs pour cicatriser les plaies de l'intestin

"Cette recherche de l’Université du Texas révèle le rôle essentiel d’un groupe de microARNs (ou miARNs) dans la suppression des tumeurs du côlon et la « cicatrisation » des maladies inflammatoires de l'intestin (MICI). Ces conclusions, présentées dans la revue Cell, ouvrent de nouvelles voies thérapeutiques pour les maladies intestinales courantes comme la colite ulcéreuse et la maladie de Crohn."

http://www.santelog.com/news/cancerologie/can...relasuite.htm#lirelasuite

COLORECTAL CANCER : Some miRNAs to heal the wounds of the intestine

"This research from the University of Texas reveals the essential role of a group of microRNAs (miRNAs or) in the suppression of colon tumors and "healing" inflammatory bowel disease (IBD). These findings, reported in the journal Cell, open new therapeutic avenues for the common intestinal diseases such as ulcerative colitis and Crohn's disease."

http://www.cell.com/cell/abstract/S0092-8674(14)00489-9

French Article
http://www.santelog.com/news/cancerologie/can...relasuite.htm#lirelasuite
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Robert Heikkinen
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Re: News XXXIII

More news from Sweden! (can someone translate pls?):

http://www.svd.se/nyheter/inrikes/cancercelle...nska-forskare_3631850.svd
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[Edit 1 times, last edit by Robert Heikkinen at Jun 6, 2014 7:06:34 AM]
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[CSF] Thomas Dupont
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Re: News XXXIII

More news from Sweden! (can someone translate pls?):

http://www.svd.se/nyheter/inrikes/cancercelle...nska-forskare_3631850.svd

New general concept for the treatment of cancer

"A team of researchers from five Swedish universities, led by Karolinska Institutet and the Science for Life Laboratory, have identified a new way of treating cancer. The concept is presented in the journal Nature and is based on inhibiting a specific enzyme called MTH1, which cancer cells, unlike normal cells, require for survival. Without this enzyme, oxidized nucleotides are incorporated into DNA, resulting in lethal DNA double-strand breaks in cancer cells."

http://ki.se/en/news/new-general-concept-for-the-treatment-of-cancer

http://www.nature.com/nature/journal/v508/n7495/full/nature13181.html
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[CSF] Thomas Dupont
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News XXXIV

1- New targets that could increase effectiveness, reduce side effects in breast cancer treatments

"New targets for potential intervention in breast cancer have been identified by researchers. These new targets could eventually increase effectiveness and reduce the undesirable side effects associated with current treatments. In addition to exploring potential new drugs for breast cancer, the researchers also hope to investigate the implications for prostate cancer, another hormone-driven disease."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

2- Short nanotubes target pancreatic cancer

"Short, customized carbon nanotubes have the potential to deliver drugs to pancreatic cancer cells and destroy them from within, according to researchers. Pristine nanotubes produced through a new process can be modified to carry drugs to tumors through gaps in blood-vessel walls that larger particles cannot fit through. The nanotubes may then target and infiltrate the cancerous cells' nuclei, where the drugs can be released through sonication -- that is, by shaking them."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

3- Why are older women more vulnerable to breast cancer ? New clues

"More insights into why older women are more susceptible to breast cancer has been gained by researchers. They found that as women age, the cells responsible for maintaining healthy breast tissue stop responding to their immediate surroundings, including mechanical cues that should prompt them to suppress nearby tumors."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

4- New therapy for pancreatic cancer patients shows promising results

"A new drug called MM-398, given in combination with 5-flourouracil and leucovorin, produced a significant overall survival rate in patients with advanced, previously-treated pancreatic cancer, a new clinical trial has demonstrated. The NAPOLI-1 (NAnoliPOsomaL Irinotecan) Phase 3 study -- a final confirmation of a drug's safety and effectiveness -- was conducted among patients with metastatic pancreatic cancer who previously received gemcitibine, which has been the standard-of-care therapy for such patients."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

5- Can mice mimic human breast cancer ? Study says 'yes'

"Many of the various models used in breast cancer research can replicate several characteristics of the human disease, especially at the gene level, researchers report. "There are definitely clear parallels between mice and men in relation to breast cancer and this study provides legitimacy to using these models so ultimately a cure can be found," one researcher said."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

6- Race could be a factor in head, neck cancer survival rates

"The national survival rates for African-Americans diagnosed with head and neck cancer have not improved in the last 40 years despite advances in the treatment and management of the disease, researchers have found. The researchers suggest that inherent genetic factors in African-Americans may make some tumors resistant to treatments. However, more research needs to be done on the subject of survival disparity in patients with head and neck cancer."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29
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alged
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News XXXV

Hope of a new way to cure eye cancerous tumor
a discovery made by american scientists of San Diego University and edited
in the review Cancer Cell

(cud somebody translate from french pls)

Une piste de traitement contre le mélanome de l’œil
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[CSF] Thomas Dupont
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Re: News XXXV

Hope of a new way to cure eye cancerous tumor
a discovery made by american scientists of San Diego University and edited
in the review Cancer Cell

(cud somebody translate from french pls)

Une piste de traitement contre le mélanome de l’œil

Eye Cancer Cause And Treatment Pathway Found In 2 Key Genes

"A new gene discovery may lead researchers to a treatment for eye cancer. Researchers at the University of California, San Diego, School of Medicine have discovered how two genetic mutations can cause the development of melanoma of the eye, which is the most common form of eye cancer. Figuring out how the genes work is only the first step in the battle to treat cancer. Researchers say now that they know, they have a promising therapeutic target for treating the disease in the future."

http://www.medicaldaily.com/eye-cancer-cause-...-found-2-key-genes-285598
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[CSF] Thomas Dupont
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News XXXVI

1- Prostate cancer biomarkers identified in seminal fluid

"Improved diagnosis and management of one of the most common cancers in men -- prostate cancer -- could result from research that has discovered that seminal fluid contains biomarkers for the disease. Results of a study have shown that the presence of certain molecules in seminal fluid indicates not only whether a man has prostate cancer, but also the severity of the cancer."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

2- Seemingly invincible cancer stem cells reveal a weakness

"Metastatic cancer cells, which can migrate from primary tumors to seed new malignancies, have thus far been resistant to the current arsenal of anticancer drugs. Now, however, researchers have identified a critical weakness that actually exploits one of these cells’ apparent strengths—their ability to move and invade tissues. Their research could inform novel approaches to screening tumors for personalized therapy or to drugs that specifically target these cells."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

3- Teenager unleashes computer power for cancer diagnosis

"She is only 19 but has already experimented with neural networks, built prototype software to help doctors diagnose breast cancer, won a $50,000 college scholarship from Google and been invited to the White House to showcase her research."

http://www.bbc.com/news/health-27518779
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[CSF] Thomas Dupont
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News XXXVII

CANCER du FOIE : Un vaccin fait ses preuves chez la souris

"Cette étude de l'Université de Géorgie Regents montre l’efficacité d’un vaccin contre le cancer du foie chez la souris. Alors que le cancer du foie est parmi les cancers les meurtriers avec un taux de survie à 3 ans de 17%, ce candidat vaccin, basé sur une protéine exprimée par les cellules de cancer du foie, présenté dans la revue Hepatology, représente une piste prometteuse. Des essais sur l’Homme sont déjà programmés."

http://www.santelog.com/news/cancerologie/can...relasuite.htm#lirelasuite
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[CSF] Thomas Dupont
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News XXXVIII

1- Prostate-cancer surgery prices are elusive

"Patients who want to compare prices for prostate-cancer surgery may find it rough going: a study has found a 13-fold difference in prices quoted by 100 hospitals across the United States. Moreover, most provided little more than broad estimates, and only three gave a hard copy of the charges."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

2- Most breast cancer patients may not be getting enough exercise

"Physical activity after breast cancer diagnosis has been linked with prolonged survival and improved quality of life, but most participants in a large breast cancer study did not meet national physical activity guidelines after they were diagnosed. Moreover, African-American women were less likely to meet the guidelines than white women. The findings indicate that efforts to promote physical activity in breast cancer patients may need to be significantly enhanced."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

3- Researchers pinpoint new role for enzyme in DNA repair, kidney cancer

"The enzyme Set2 is a major player in DNA repair, a complicated and crucial process that can lead to the development of cancer cells if the repair goes wrong. "We found that if Set2 is mutated, DNA repair does not properly occur" said one researcher. "One consequence could be that if you have broken DNA, then loss of this enzyme could lead to downstream mutations from inefficient repair. We believe this finding helps explain why the human version of Set2 -- which is called SETD2 -- is frequently mutated in cancer."."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

4- African-American women more likely to be diagnosed with higher risk breast cancer

"African-American women frequently present with biologically less favorable subtypes of breast cancer, a study has shown. Researchers used genomic tests in their research; unlike genetic tests, such as those for BRCA genes, genomic tests look at the genes inside a breast cancer cell and how strongly they are expressed. The findings support prior research that has looked at the biologic characteristics of breast cancer in African-American women."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

5- Longer telomeres linked to risk of brain cancer: Double-edged sword, gene variants may promote overall health while increasing risk of gliomas

"New genomic research reveals that two common gene variants that lead to longer telomeres, the caps on chromosome ends thought by many scientists to confer health by protecting cells from aging, also significantly increase the risk of developing the deadly brain cancers known as gliomas."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

6- Endoscope with oxygen sensor detects pancreatic cancer

"An optical blood oxygen sensor attached to an endoscope is able to identify pancreatic cancer in patients via a simple lendoscopic procedure, according to researchers. The study shows that the device, which acts like the well-known clothespin-type finger clip used to measure blood oxygen in patients, has a sensitivity of 92 percent and a specificity of 86 percent."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29
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[CSF] Thomas Dupont
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News XXXIX

Les vrais défis du quotidien après le diagnostic

"Composer avec le risque de rechute, les effets secondaires de la maladie et des traitements, mais aussi avec les nécessités de reprise de la vie quotidienne, la vie n’est pas simple après un diagnostic de cancer, constate cette enquête, VICAN2 -pour « Vie après le Cancer à deux ans du diagnostic »- menée par l’Institut national du Cancer auprès de auprès de 4.349 personnes... Des conclusions qui, en France, dans un contexte d’augmentation des cancers, concernent plus de 3 millions de personnes."

http://www.santelog.com/news/cancerologie/can...relasuite.htm#lirelasuite

http://www.e-cancer.fr/publications/99-recher...-lannonce-a-lapres-cancer
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