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Forum: Mapping Cancer Markers Forum
Thread: The Cancer Daily News : Stay connected to the latest news |
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Thread Status: Active Total posts in this thread: 178
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Targets for immunotherapy in early-stage breast cancer
----------------------------------------"A new molecular analysis tool has been used to detect the level of an important target for immunotherapy in early-stage breast cancers, researchers report. The diagnostic test, using RNAScope, measures the amount of PD-L1 mRNA in cancer tissues and is devoid of many of the technical issues that plague antibody-based detection methods that have yielded conflicting results in the past. PD-L1 is the target of several novel immune stimulatory therapies in clinical trials." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 2- Random nature of metastasis revealed by physicists "The spreading of a cancerous tumor from one part of the body to another may occur through pure chance instead of key genetic mutations, a new study has shown. Physicists have used a statistical model to show that the formation of a new secondary tumor -- commonly known as a metastasis -- could just as likely derive from "common" cancer cells that circulate in the bloodstream, as from "specialist" cancer cells." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 3- Bowel cancer breakthrough may benefit thousands of patients "A significant breakthrough has been made that may benefit patients with bowel cancer. Researchers have discovered how two genes cause bowel cancer cells to become resistant to treatments used against the disease. The activity of the two genes, called MEK and MET, was uncovered when the researchers looked at all the different pathways and interactions taking place in bowel cancer cells." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 4- New gene discovered that stops spread of deadly cancer: Scientists identify gene that fights metastasis of a common lung cancer "A gene responsible for stopping the movement of cancer from the lungs to other parts of the body has been discovered by researchers, indicating a new way to fight one of the world’s deadliest cancers. By identifying the cause of this metastasis, which often happens quickly in lung cancer and results in a bleak survival rate, scientists are able to explain why some tumors are more prone to spreading than others. The newly discovered pathway may also help researchers understand and treat the spread of melanoma and cervical cancers." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Negative HPV test may predict lower cervical cancer risk than a negative Pap
----------------------------------------"In the US, cotesting for human papilloma virus and Pap testing for cervical cancer every 5 years for women aged 30-65 years is now recommended. However, human papilloma virus testing alone may provide better reassurance against cervical cancer than Pap testing alone and similar reassurance to cotesting, according to a study." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 2- Described novel regulator of protein inactive in over 50 percent of human tumors "The interaction between HERC2 proteins with another protein called p53 is inactivated in more than half of human tumors, researchers have discovered. The study suggests that mutations in HERC2 also may be associated with cancer in humans. "In the laboratory we have observed that without HERC2 cells increases proliferation. It's the same effect as if they inactivated p53" says the lead author." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 3- First study worldwide to show higher concentration of trace elements in bone cancer "In a study that is the only one of its kind worldwide, researchers have investigated the distribution of trace elements in the tissue of bone tumors. The result: tumor tissue contains higher concentrations of trace elements. This could represent a starting point for the development of targeted therapies for bone cancer." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 4- Genetic cause of common breast tumors found "A major breakthrough in understanding the molecular basis of fibroadenoma, one of the most common breast tumors diagnosed in women, has been made by a multidisciplinary team of scientists. The team used advanced DNA sequencing technologies to identify a critical gene called MED12 that was repeatedly disrupted in nearly 60 percent of fibroadenoma cases." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 5- Metabolic enzyme stops progression of most common type of kidney cancer "An enzyme called FBP1 -- essential for regulating metabolism -- binds to a transcription factor in the nucleus of certain kidney cells and restrains energy production in the cell body, researchers report. What's more, they determined that this enzyme is missing from all kidney tumor tissue analyzed. These tumor cells without FBP1 produce energy at a much faster rate than their non-cancer cell counterparts." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 6- Scientists map one of most important proteins in life -- and cancer "Scientists reveal the structure of one of the most important and complicated proteins in cell division -- a fundamental process in life and the development of cancer -- in a new research article. Images of the gigantic protein in unprecedented detail will transform scientists' understanding of exactly how cells copy their chromosomes and divide, and could reveal binding sites for future cancer drugs." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Understanding how neuro cells turn cancerous
----------------------------------------"New research, for the first time, brings scientists nearer to understanding how some cells in the brain and nervous system become cancerous. The team studied a tumor suppressor called Merlin. Their results have identified a new mechanism whereby Merlin suppresses tumors, and that the mechanism operates within the nucleus. The research team has discovered that unsuppressed tumor cells increase via a core signalling system, the hippo pathway, and they have identified the route and method by which this signalling occurs." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 2- Viral therapy could boost limb-saving cancer treatment "Viruses designed to target and kill cancer cells could boost the effectiveness of chemotherapy to the arms and legs and help avoid amputation, a new study reports. Researchers tested the effectiveness of a genetically engineered version of the virus used to vaccinate against smallpox. They found use of the virus alongside isolated limb perfusion chemotherapy -- given directly to blood vessels supplying the affected arm or leg as an alternative to amputation -- was more effective in rats than either treatment on its own." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 3- New, accurate epigenetic test could eliminate unnecessary repeat biopsies for prostate cancer "More than one million prostate biopsies are performed each year in the U.S., including many repeat biopsies for fear of cancer missed. Therefore there is a need to develop diagnostic tests that will help avoid unnecessary repeat biopsies. Two independent trials have now validated the performance of an epigenetic test that could provide physicians with a better tool to help eliminate unnecessary repeat prostate biopsies, report investigators." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 4- Anti-cancer drug kicks HIV out of hiding "An anti-cancer drug can activate hidden HIV, a pilot study by HIV researchers has shown. The researchers found that the anti-cancer drug romidepsin increased the virus production in HIV-infected cells between 2.1 and 3.9 times above normal and that the viral load in the blood increased to measurable levels in five out of six patients with HIV infection." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Genetics of cancer: Non-coding DNA can finally be decoded
----------------------------------------"Cancer is a disease of the genome resulting from a combination of genetic modifications, or mutations. We inherit from our parents strong or weak predispositions to developing certain kinds of cancer; in addition, we also accumulate new mutations in our cells throughout our lifetime. Although the genetic origins of cancers have been studied for a long time, researchers were not able to measure the role of non-coding regions of the genome until now." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 2- Presence of uterine cancers at time of hysterectomy studied using morcellation "Among women undergoing a minimally invasive hysterectomy using electric power morcellation, uterine cancers were present in 27 per 10,000 women at the time of the procedure, according to a study. There has been concern that this procedure, in which the uterus is fragmented into smaller pieces, may result in the spread of undetected malignancies." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 3- Lacking trust in one's doctor affects health of emotionally vulnerable cancer patients "The physical and mental well-being of people with cancer may be affected by how they feel about their relationship with their physician and by differences in attachment styles, finds a new study. Patients who feel anxious and uneasy with their doctor may be impacted the most. "Anxiously attached patients may experience and report more physical and emotional problems when the relationship with their physician is perceived as less trusting," said the lead author." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 4- Pathogenic connection between autoimmune disorders, cancer found "Autoimmune disorders may share certain pathogenic mechanisms with cancer, according to a new report. "This study opens a new therapeutic approach for myasthenia gravis, as well as other autoimmune disorders," said one researcher. "Conventional therapies may improve the disease, but have numerous complications. This discovery may lead to a viable treatment option for the millions of American suffering from these disorders."." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Cancer: Treatment that prevents tumor metastasis identified in animal study
----------------------------------------"Metastasis, the strategy adopted by tumor cells to transform into an aggressive form of cancer, are often associated with a gloomy prognosis. Managing to block the metastasis or, even better, prevent their formation would be a giant step towards the fight against cancer. Researchers successfully performed this on models of human tumors in mice." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 2- Metastatic brain tumor treatment could be on the horizon with use of SapC-DOPS "A new study has provided hope that previously studied SapC-DOPS could be used for treatment of brain cancer that has spread. "These results support the potential of SapC-DOPS for the diagnosis and therapy of primary and metastatic brain tumors which is critically needed to increase survival rates of patients with this illness,â one researcher said." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 3- Natural products from plants protect skin during cancer radiotherapy "Plant-derived natural product chemicals could offer protection to the skin from the harmful effects of gamma radiation during cancer radiotherapy, suggests research." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
CANCER du SEIN : L'obscurité totale la nuit, une clé de la réussite du traitement
----------------------------------------"L'obscurité totale la nuit, la clé de la réussite du traitement du cancer du sein ? Une conclusion a priori surprenante de cette étude de l’Université de Tulane (Nouvelle-Orléans). Elle s’explique pourtant par l’intervention de l’hormone du sommeil, la mélatonine, dans l’efficacité du traitement par tamoxifène et par la perturbation du rythme circadien et de la production de cette hormone, en cas d’exposition nocturne à la lumière. Des conclusions, publiées dans la revue Cancer Research, primordiales pour les patientes et leurs cliniciens." http://www.santelog.com/news/cancerologie/can...relasuite.htm#lirelasuite BREAST CANCER : Total darkness at night is key to success of breast cancer therapy "Exposure to light at night, which shuts off nighttime production of the hormone melatonin, renders breast cancer completely resistant to tamoxifen, a widely used breast cancer drug, says a new study by Tulane University School of Medicine cancer researchers. The study, "Circadian and Melatonin Disruption by Exposure to Light at Night Drives Intrinsic Resistance to Tamoxifen Therapy in Breast Cancer," published in the journal Cancer Research, is the first to show that melatonin is vital to the success of tamoxifen in treating breast cancer." http://www.eurekalert.org/pub_releases/2014-07/tu-tda072214.php French Article http://www.santelog.com/news/cancerologie/can...relasuite.htm#lirelasuite |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Test increases odds of correct surgery for thyroid cancer patients
----------------------------------------"The routine use of a molecular testing panel increases the likelihood of performing the correct initial surgery for thyroid cancer patients by 30 percent, researchers report. "Before this test, about one in five potential thyroid cancer cases couldn't be diagnosed without an operation to remove a portion of the thyroid," said the lead author." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 2- Nanoparticle 'alarm clock' tested to awaken immune systems put to sleep by cancer "Researchers are exploring ways to wake up the immune system so it recognizes and attacks invading cancer cells. One pioneering approach uses nanoparticles to jumpstart the body’s ability to fight tumors. Nanoparticles are too small to imagine. One billion could fit on the head of a pin. This makes them stealthy enough to penetrate cancer cells with therapeutic agents such as antibodies, drugs, vaccine type viruses, or even metallic particles." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 3- Informed consent: False positives not a worry in lung cancer study "A false positive screen result -- a screening test in which initial findings of concern for cancer are later found not to be worrisome -- did not cause participants undue anxiety or reduced quality of life, a new study shows. Researchers hypothesize that clear and accurate consent forms prepared patients for these false positive diagnoses." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 4- Is Europe putting cancer research at risk? "Experts have expressed concern that the proposed EU General Data Protection Regulation could make cancer research impossible and add a significant burden to both doctors and cancer patients. The proposed wording of the regulation stipulates ‘explicit and specific patient consent’, meaning that researchers would have to approach patients every single time research is planned in order to consult their data or use tissue samples stored for research purposes." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 5- Brain tumor causes, risk factors elude scientists "Today, nearly 700,000 people in the U.S. are living with a brain tumor, and yet, when it comes to pinpointing causes or risk factors, scientists are still searching for answers. "Unlike the strong correlation between smoking and lung cancer, we just haven't found a specific risk factor like that for brain tumors," said a researcher. "We have determined that ionizing radiation to the head is a risk factor when received in therapeutic doses, but even in those cases, the risk of developing a brain tumor is low."." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- New drug target can break down cancer's barrier against treatment
----------------------------------------"Targeting a molecule in blood vessels can make cancer therapy significantly more effective, according to research. Researchers have found that a molecule, called focal adhesion kinase (FAK), signals the body to repair itself after chemotherapy or radiotherapy, which kill cancer cells by damaging DNA. When the researchers removed FAK from blood vessels that grew in melanoma or lung cancer models, both chemotherapy and radiation therapies were far more effective in killing the tumors." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 2- Epigenetic changes can drive cancer, study shows "A mouse model has been created providing the first in vivo evidence that epigenetic alterations alone can cause cancer. Epigenetic alterations don't change the DNA sequence but how it is 'read.' In particular, DNA methylation, the addition of a methyl group (or molecule), is an epigenetic switch that can stably turn off genes, suggesting the potential to cause cancer just as a genetic mutation can. Until now, direct evidence that DNA methylation drives cancer formation was lacking." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 3- Clearing cells to prevent cervical cancer "A novel approach to preventing cervical cancer has been described by researchers, based on findings showing successful reduction in the risk of cervical cancer after removal of a discrete population of cells in the cervix. The findings come from a study that looked at squamocolumnar junction cells, or SCJ cells. These cells reside in the cervical canal and have been implicated as the origins of cervical cancer." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 4- Gene changes in breast cancer cells pinpointed with new computational method "Computer scientists working with high-throughput data generated by breast cancer biologists have devised a computational method to determine how gene networks are rewired as normal breast cells turn malignant and as they respond to potential cancer therapy agents." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 5- New way to determine cancer risk of chemicals found "It is possible to predict long-term cancer risk from a chemical exposure by measuring the short-term effects of that same exposure, new research has found. The findings will make it possible to develop simpler and cheaper tests to screen chemicals for their potential cancer causing risk." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Potential 'universal' blood test for cancer discovered
----------------------------------------"A simple blood test that can be used to diagnose whether people have cancer or not has been devised by researchers. The test will enable doctors to rule out cancer in patients presenting with certain symptoms, saving time and preventing costly and unnecessary invasive procedures such as colonoscopies and biopsies being carried out. Alternatively, it could be a useful aid for investigating patients who are suspected of having a cancer that is currently hard to diagnose." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 2- Lifestyle choices may affect long-term heart health of childhood cancer survivors "Following a healthy lifestyle may lower childhood cancer survivors’ risk of developing the metabolic syndrome, a study shows. The findings indicate that children with cancer and adults who had cancer when they were children should receive information about how their lifestyle may influence their long-term health." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 ---------------------------------------- [Edit 1 times, last edit by [CSF] Thomas Dupont at Jul 31, 2014 4:13:58 PM] |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Do your stem cells sound like cancer? While-you-wait, non-invasive cancer diagnosis by converting stem cell data into sound
----------------------------------------"Converting stem cell data into sounds could enable GPs to make instant, non-invasive cancer diagnoses during a routine check-up. A recent study shows how data sonification (where data is conveyed as audio signals as opposed to visual illustrations such as graphs) can improve standard techniques currently used in spectroscopy stem cell analysis. What could this mean for cancer diagnostics?" http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 2- Irreversible inhibitor for KRAS gene mutation involved in lung, colon, and pancreatic cancers "Cancer researchers have found a molecule that selectively and irreversibly interferes with the activity of a mutated cancer gene common in 30 percent of tumors." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 3- Genetic mutations linked to salivary gland tumors "Research conducted at the Florida campus of The Scripps Research Institute has discovered links between a set of genes known to promote tumor growth and mucoepidermoid carcinoma, an oral cancer that affects the salivary glands." http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29 |
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