1- Surgical treatment for metastatic melanoma of the liver increases overall survival

"Surgical resection markedly improves survival among metastatic melanoma patients whose disease is isolated to a few areas in the liver, according to a new study. The bottom line, according the researchers, is that surgeons should discuss surgical resection for the treatment of melanoma liver metastases with their patients if their disease is limited to a few areas in the liver, their overall health status is good, and the disease is indolent or the patients are responding to systemic therapy."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

2- Combatting drug resistance for melanoma patients

"A new way to identify possible therapeutic targets for patients with drug resistant melanoma has been developed by researchers. It involves using liquid chromatography-multiple reaction monitoring mass spectrometry to measure biomarkers or molecules in blood and tissue that indicates cancer is present. These measurements can help researchers determine if a patient is responding to treatment."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

3- Single gene separates aggressive, non-aggressive lymphatic system cancer

"For a rare form of cancer called thymoma, researchers have discovered a single gene defining the difference between a fast-growing tumor requiring aggressive treatment and a slow-growing tumor that doesn't require extensive therapy. Most of the diagnosed patients have surgery, but, depending on the presumed aggressiveness of the cancer, some patients will have radiation and/or chemotherapy in addition or instead of surgery."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

4- More than 40 melanoma-specific genes that determine aggressiveness identified

"More than 40 genes have been identified that predict the level of aggressiveness of melanoma and that distinguish it from other cancers with a poor prognosis, researchers report. This study is relevant because it explains why a drug is being used to selectively attack the melanoma tumor cells. Melanoma is one of the worst, most metastatic cancers known today."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

1- Free mobile app for thyroid calculator on Apple iPhone and iPad

"The thyroid calculator for rapid calculation of: Calcitonin and Carcinoembryonic Antigen Doubling Time; Thyroid Nodule Volume change; Thyroid Cancer Staging. Calculation results are not preserved within the app, thus maintaining patient privacy and security."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

2- Drug everolimus does not improve overall survival in patients with advanced liver cancer

"Despite strong preclinical data, the drug everolimus failed to improve overall survival in patients with advanced liver cancer, compared to placebo, according to a study. Patients with advanced hepatocellular carcinoma (HCC; a type of liver cancer) have a median overall survival of less than l year, largely because of the absence of effective therapies."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

3- Proton therapy has advantages over IMRT for advanced head, neck cancers

"A new study by radiation oncologists comparing the world's literature on outcomes of proton beam therapy in the treatment of a variety of advanced head and neck cancers of the skull base compared to intensity modulated radiation therapy (IMRT) has found that proton beam therapy significantly improved disease free survival and tumor control when compared to IMRT."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

4- Treasure trove of genes key to kidney cancer revealed by research

"A genomic analysis of clear cell renal cell carcinoma, the most common form of kidney cancer, from 72 patients has uncovered 31 genes that are key to development, growth and spread of the cancer, say researchers. This study is the most extensive analysis to date of gene expression's role in ccRCC tumor growth and metastasis. The ccRCC subtype accounts for 80 percent of all kidney cancer cases."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

5- Chinese herbal extract may help kill off pancreatic cancer cells

"The herbal extract triptolide has been used on human pancreatic cancer cells and tissue in culture by researchers. Administration of the herb decreased GRP78 protein in the cells, thereby reducing cancer cell survival and facilitating cell death. A diagnosis of pancreatic cancer—the fourth most common cause of cancer death in the U.S.—can be devastating. Due in part to aggressive cell replication and tumor growth, pancreatic cancer progresses quickly and has a low five-year survival rate (less than 5 percent)."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

6- European solution for effective cancer drug development presented

"Experts describes how collaborative molecular screening platforms can help researchers understand the biology of a cancer and support the design and conduct of subsequent confirmatory trials. Collaborative molecular screening platforms offer a high quality integrated infrastructure for efficient screening of patients with cancer for specific molecular alterations. These identified alterations will define target populations for early trials with novel targeted agents."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

7- Enlightening cancer cells with optogenetics

"The first application of optogenetics to cancer research has been conducted on engineered cell surface receptors activated by light, researchers report. Small algal protein domains serve as synthetic light sensors in human cells."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

8- Inhibition of protein opens door to treatment of pancreatic cancer

"A new protein, galectin-1, has been identified as a possible therapeutic target for pancreatic cancer. For the first time, researchers have demonstrated the effects of the inhibition of this protein in mice suffering this type of cancer and the results showed an increase in survival of 20%. The work further suggests that it could be a therapeutic target with no adverse effects."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

9- Cancer mutations identified as targets of effective melanoma immunotherapy

"A new approach demonstrated that the recognition of unique cancer mutations appeared to be responsible for complete cancer regressions in two metastatic melanoma patients treated with a type of immunotherapy called adoptive T-cell therapy. This new approach may help develop more effective cancer immunotherapies, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

10- Cancer risk: Aspirin and smoking affect aging of genes

"The risk of developing cancer increases with age. Outside factors can affect that risk, like smoking, which increases cancer risk, and regular aspirin use, which has been shown to decrease it. Now researchers have demonstrated the change in risk connected to colorectal cancer with regard to aspirin use. Numerous studies have confirmed the protective effect of the drug against different types of cancer, including reducing the risk to develop colorectal cancer by an average of 40%. However, it is unknown how exactly the drug influences the cancer risk."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

11- People with HIV with early-stage cancers are up to four times more likely to go untreated for cancer

"People with HIV who are diagnosed with cancer are two to four times more likely to go untreated for their cancer compared to uninfected cancer patients, according to a new, large retrospective study. Life expectancy for HIV-infected people is now similar to uninfected people, but survival for HIV patients who develop cancer is not. While many studies have attempted to understand why HIV-infected cancer patients have worse outcomes, the new study examined differences in cancer treatment as one potential explanation."

http://www.sciencedaily.com/releases/2014/06/...ily%3A+Top+Health+News%29

Cancer du sein : la mammographie 3D fait ses preuves

"Des chercheurs de Philadelphie viennent de publier la plus grande étude jamais produite sur l’efficacité de la mammographie 3D. Cette technique, qui détecte 30 % de plus de cancers du sein, est plus fiable que la classique mammographie. Peut-être s’invitera-t-elle, à terme, dans le programme national de dépistage généralisé."

http://www.futura-sciences.com/magazines/sant...ie-3D-fait-ses-preuves%5D

Breast cancer : 3D mammography proven

"Researchers in Philadelphia have published the largest study ever produced on the effectiveness of the 3D mammogram. This technique, which detects more than 30% of breast cancer, is more reliable than the conventional mammography. Perhaps she will invite ultimately in the national program of universal screening."

http://jama.jamanetwork.com/article.aspx?articleid=1883018

French Article
http://www.futura-sciences.com/magazines/sant...ie-3D-fait-ses-preuves%5D

1- Safer, cheaper building blocks for future anti-HIV and cancer drugs

"Researchers have developed an economical, reliable and heavy metal-free chemical reaction that yields fully functional 1,2,3-triazoles. Triazoles are chemical compounds that can be used as building blocks for more complex chemical compounds, including pharmaceutical drugs."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

2- Tool helps guide brain cancer surgery

"A tool to help brain surgeons test and more precisely remove cancerous tissue was successfully used during surgery. The mass spectrometry tool sprays a microscopic stream of charged solvent onto the tissue surface to gather information about its molecular makeup and produces a color-coded image that reveals the location, nature and concentration of tumor cells."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

CANCER pédiatrique : Congeler le tissu testiculaire pour préserver la fertilité

"Les taux de guérison des cancers pédiatriques augmentent, mais leurs traitements, comme la chimiothérapie peuvent entraîner l'infertilité. Préserver la fertilité des garçons pré-pubères touchés par ces cancers est un véritable défi. Celui de ces chercheurs japonais qui démontrent, dans la revue Nature Communications, et sur la souris, que la cryoconservation de tissu testiculaire est une mesure réaliste pour préserver la fertilité d'un individu."

http://www.santelog.com/news/sexualite/cancer...relasuite.htm#lirelasuite

Pediatric CANCER : Freezing testicular tissue to preserve fertility

"Cure rates of pediatric cancers are increasing, but their treatments, such as chemotherapy can cause infertility. Preserve the fertility of prepubertal boys affected by these cancers is challenging. One of these Japanese researchers demonstrate in the journal Nature Communications, and on the mouse, that the cryopreservation of testicular tissue is a realistic measure to preserve the fertility of an individual."

http://www.nature.com/ncomms/2014/140701/ncomms5320/full/ncomms5320.html

French Article
http://www.santelog.com/news/sexualite/cancer...relasuite.htm#lirelasuite